Overview
Tcontacts (Tcons: Tertiary Contacts) allows for a fast and accurate analysis internal protein interactions.
Given a PDB file to upload your own file (specifying PDB functionality under construction) and the chain of interest, TCons will provide a graphical representation of the residues in tertiary contact.
The contact map will not only indicate the internal contacts present, but will also indicate whether the contact is a
packing interaction,
hydrogen bond,
ion pair or
salt bridge (hydrogen-bonded ion pair).
Contact maps allow for easy visualization and comparison of the internal packing between proteins.
Execute Tcons
Reference:
Tsai, J., and Levitt, M.
(2002) Evidence of turn and salt bridge contributions to beta-hairpin stability: MD simulations of C-terminal fragment from the B1 domain of protein G.
Biophys Chem 101-102, 187-201.